Chemical exposure and intestinal function.

نویسنده

  • C M Schiller
چکیده

The particular substances that are ingested by individuals are the consequence of their environmental, residential, and occupational exposures. The possible effects of these exposures on intestinal functions can be examined by the evaluation of in vivo or in vitro exposure followed by an in vivo and/or in vitro monitoring of effects. Several examples of the in vivo exposure and in vitro monitoring approach are presented to demonstrate the consequences of oral exposure to either a heavy metal (arsenic), or a herbicide contaminant (2,3,7,8-tetrachlorodibenzo-p-dioxin) or a jet fuel propellant (hydrazine) and the subsequent measurement of either a particular metabolic pathway, or a cell-specific enzyme induction or the development of brush border enzymes are presented.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Survival of Probiotics in Synbiotic Apple Juice During Refrigeration and Subsequent Exposure to Simulated Gastro-Intestinal Conditions

The aim of this work was to produce synbiotic apple juice and investigate the survival of Lactobacillus acidophilus and Lactobacillus plantarum in apple juice during the refrigerated storage (4 °C) for 42 days and then the ability of the mentioned probiotic bacteria in gastrointestinal tolerance under gastrointestinal tract conditions, with simulated gastric and bile juices. Eight-...

متن کامل

Reproductive Function In Men Following Exposure to Chemical Warfare Containing Sulfur Mustard

  SUMMARY In order to investigate acute and chronic effects of exposure to warfare containing mustards in young men, the time course of changes in serum concentrations of total and free testosterone, dehydroepiandrosterone (DS), FSH, LH and prolactin was evaluated in 16 men in the first 3 months and testicular function in 42 men one to three years after injury. Serum total and free testostero...

متن کامل

ارزیابی اثرات تنفسی مواجهه شغلی با سموم آفت کش

Background: Pesticides are chemical compounds used against vectors of human and animal diseases as well as plant pests. This study was undertaken to assess pulmonary reactions, if any, associated with occupational exposure to pesticides. Methods: This was a cross sectional analytical study in which a group of 86 exposed (employees of a pesticide producing company) and 75 unexposed referent sub...

متن کامل

Chemical and biochemical implications of human and animal exposure to toxic substances in food.

The complexities of the subject of food toxicants are surveyed in regard to their qualitative and quantitative aspects. Chemical and biochemical implications are reviewed, tracing the stages in the transit through the body of chemical entities in food. The capacity of the intestinal flora to bring about chemical transforma.. tions of ingested compounds may lead to detoxication or serve to creat...

متن کامل

Long Term Effects of Mustard Gas on Pulmonary Function Tests in Chemical Warfare Victims in Kerman, Iran

Iraq has used extensively chemical warfare agents in recent Iran-Iraq conflict (1980-1988) and it is believed about 450,000 people were exposed to this agents. Long-term effects of chemical warfare agents, particularly mustard gas, on pulmonary function tests (PFT) (VC, FEV1 , FVC, FEV/FVC, PEF, MEF50%, MEF25%, MEF25-75% , ERC and IC) are estimated during 7.7 [standard deviation (SD)=l.2] years...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Environmental Health Perspectives

دوره 33  شماره 

صفحات  -

تاریخ انتشار 1979